Accessible PDF for Windows

Peter Verhoeven at magnifers.org has a good review of a new open sourced application called Accessible PDF. It makes PDFs accessible by using an component called PDFtoHTML to convert the text into a structured format that is easily manipulated and read by screenreaders. It's ability to change colours and line spacing also makes it useful for low vision users or users with dyslexia. More information is available on the Accessible PDF page. Alternatively you can download it directly.